Fig. 4: Substrate scope of heteroarenes.
From: Multicomponent double Mannich alkylamination involving C(sp2)–H and benzylic C(sp3)–H bonds
Reactions were carried out under condition A. Yields refer to isolated products. N(Phth) = N-phthalimide. a3a was replaced with propargylamine hydrochloride under condition B. b5s was prepared from 5r via click reaction.
