Fig. 5: CRP weighted GRS PheWAS Manhattan plot.
From: Genetic analysis of over half a million people characterises C-reactive protein loci

The red line indicates the Bonferroni threshold (p < 4.47 × 10−5) and the blue line indicates the nominal threshold (p < 0.05). The triangle pointing up represents positive association and down a negative association. All FDR significant phenotypes are annotated (FDR q < 0.05).