Fig. 4: Purified Als fusion proteins are direct TIGIT ligands. | Nature Communications

Fig. 4: Purified Als fusion proteins are direct TIGIT ligands.

From: Candida albicans evades NK cell elimination via binding of Agglutinin-Like Sequence proteins to the checkpoint receptor TIGIT

Fig. 4

A microscale Thermophoresis experiment analyzing the interactions between fluorescently labeled TIGIT-Ig and either PVR-Ig (teal), NT-Als6-Ig (red), NT-Als7-Ig (green), NT-Als9-2-Ig (dark blue) or a negative control protein fused to an Ig tag (Control-Ig, orange). Shown are a graph and a summary table. n = 2–4 replicates derived from two biologically independent experiments. Error bars represent the standard error of the mean. NB = No Binding.

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