Fig. 3: Model performance and feature distribution in the discovery and replication cohorts.
From: Nasal DNA methylation at three CpG sites predicts childhood allergic disease
The ROC curve and AUC of the model in the discovery cohort (a) and replication cohorts: EVA-PR (b, mean age 16 years), COPSAC2010 (c, mean age 6 years), and MAKI (d, mean age 6 years). The DNA methylation levels of the three CpG sites in participants with and without allergy are shown in (e–h), for PIAMA (e, n = 348), EVA-PR (f, n = 481), COPSAC2010 (g, n = 503), and MAKI (h, n = 259), respectively. Box plots show medians and the first and third quartiles (the 25th and 75th percentiles), respectively. The upper and lower whiskers extend the largest and smallest value no further than 1.5 × IQR, with individual dots indicating individual observations outside this range.
