Fig. 3: Relationship between DNA methylation and cfDNA size.
From: DNA methylation analysis explores the molecular basis of plasma cell-free DNA fragmentation
a, b In control subjects, (a) size distribution of hyper-and hypo-methylated cfDNA reads, (b) orientation-aware fragmentation end distribution for hyper- and hypo-methylated cfDNA in the nucleosomal context in chr12p11.1 loci; (c, d) HCC patients, (e, f) lung adenocarcinoma patients. g–i Genomewide distribution of cfDNA size and methylation level: (g) control subjects, (h) HCC patients, (i) lung adenocarcinoma patients.
