Fig. 2: Fecal concentration of acetate in Co-WT mice increases and B.pseudolongum NjM1 produces acetic acid.
From: Microbiota-derived acetate enhances host antiviral response via NLRP3
a–c Cross-validated OPLS-DA scores plots (a) and the corresponding loadings plots (b) and heat map (c) of feces extracts data from Single-WT mice and Co-WT mice on day 39 after co-housing with Nlrp3−/− mice. (n = 10 per group. OPLS-DA: Q2 = 0.224. CV-ANOVA: P = 0.041). 5-AP, aminopentanoate; TMA, trimethylamine. d The concentrations of SCFAs from B. pseudolongum NjM1 conditioned supernatant were measured using gas chromatography, and the amounts are presented as milligram per milliliter of supernatant. Results represent three independent experiments (d). Data in (d) are presented as mean ± SEM, two-tailed Student’s t test. Significant values are defined by *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Source data are provided as a Source Data file.
