Fig. 3: Genomic similarity between GEMS non-DEC fecal isolates and previously described pathotype E. coli associated with severe diarrhea. | Nature Communications

Fig. 3: Genomic similarity between GEMS non-DEC fecal isolates and previously described pathotype E. coli associated with severe diarrhea.

From: Genomic diversity of non-diarrheagenic fecal Escherichia coli from children in sub-Saharan Africa and south Asia and their relatedness to diarrheagenic E. coli

Fig. 3

a Circular plot comparing the gene content of the previously described GEMS ST-ETEC isolate 50483817 associated with a severe case of diarrhea to a GEMS non-DEC fecal isolate from a child with no diarrhea, and ETEC pathotype reference genomes that were all identified with as ST173. BSR values indicate the presence (blue), divergent similarity (yellow/green), and absence (red) of the 504838 genes among the other ST173 genomes. The largest segment of the plot is the chromosome and smaller segments are the two plasmids of ETEC isolate 504838 (p504838_108 and p504838_88). The label adjacent to each chromosome track indicates the type of genome: GEMS isolate from a control (light blue) and ETEC pathotype references (gray). b Circular plot comparing the gene content of the O104:H4 outbreak strain E. coli C227-1125 to a GEMS non-DEC fecal isolate and other pathotype reference genomes of the ST678 lineage. The BSR values indicate the absence (red), divergent similarity (yellow/green), and presence (blue) of the C227-11 genes among the other genomes. The largest segment of the plot is the chromosome and smaller segments are each of the C227-11 plasmids. The label adjacent to each chromosome track indicates the type of genome: GEMS non-DEC fecal isolate from a case (orange) and two EAEC pathotype reference genomes (gray). BSR values that served as input for the plots are provided in Supplementary Data Set 4.

Back to article page