Fig. 2: Structure of the InsP6-activated VTC complex. | Nature Communications

Fig. 2: Structure of the InsP6-activated VTC complex.

From: The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex

Fig. 2

a–c Overall structure of Vtc1/Vtc3/Vtc4R264A/R266A/E426N in complex with InsP6. Surface (Top) and cartoon (Bottom) representations are displayed in the same perspective. Vtc3 and Vtc4 are colored in blue and pink, respectively. The protomer A, B, and C of Vtc1 are colored separately in gradient green. Molecules of InsP6, phosphate and lipid are shown in stick representations. The exit tunnel of catalytic TTMVtc4 and the entrance channel of the trans-membrane region are marked with white arrows.

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