Fig. 3: Nicotine promoted SIRT1 binding with NAMPT in aged mice. | Nature Communications

Fig. 3: Nicotine promoted SIRT1 binding with NAMPT in aged mice.

From: Nicotine rebalances NAD+ homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity

Fig. 3

a Schematic diagram of the levels of NAMPT interaction with SIRT1 in various tissues (the bars represent the mean value of NAMPT-SIRT1 binding levels). The binding of SIRT1 and NAMPT in different tissues: b Cortex and Hippocampus, c Heart, d Liver, e Muscle, f Kidney. Statistical diagram of NAMPT acetylation levels of different tissues: g is a quantification of b (Cortex and Hippocampus), h is a quantification of c (Heart), i is a quantification of d (Liver), j is a quantification of e (Muscle), k is a quantification of f (Kidney). Data are means ± SEM (n = 3–4, biologically independent samples/group); p values were determined by one-way ANOVA with Tukey’s multiple comparisons test (g–k).

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