Fig. 7: Nicotine improved the OCR and ECAR in NAMPT-K53Q mutation cells. | Nature Communications

Fig. 7: Nicotine improved the OCR and ECAR in NAMPT-K53Q mutation cells.

From: Nicotine rebalances NAD+ homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity

Fig. 7

The effects of nicotine on OCR measurement a and ECAR measurement b in BV2 cells (n = 3, biologically independent samples/group). The effects of nicotine on OCR measurement c and ECAR measurement d in HT22 cells (n = 2–3, biologically independent samples/group). The quantitative analysis of OCR including, basal respiration, ATP-linked respiration, proton leak, maximal respiration, spare respiratory capacity, non-mitochondrial oxygen consumption. The quantitative analysis of ECAR including, glycolysis, glycolytic capacity, glycolytic reserve and non-glycolytic acidification. Data are means ± SEM. p values were determined by one-way ANOVA with Tukey’s multiple comparisons tests (a–d).

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