Fig. 4: Activation of GPR174.
From: Structural basis of lysophosphatidylserine receptor GPR174 ligand recognition and activation
a A comparison of active GPR174 with the inactive P2Y1 (PDB: 4xnw), ML056-bound S1PR1 (PDB:3v2y), and ONO-97808307-bound LPAR1 (PDB:4z34). b A comparison of the NPxxY motif between the active GPR174 and the inactive P2Y1, S1PR1, and LPAR1. c A comparison of the DRY motif between the active GPR174 and the inactive P2Y1, S1PR1, and LPAR1.
