Fig. 3: The active site of NDV L-P complex.
From: Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein
a The RdRp region is highlighted in colors: the finger is shown in cyan, the thumb in pale yellow, the palm in light pink and the remaining structure of L is colored in gray. b Similar view as shown in a, and motifs A–F are highlighted in unique colors. c Configuration of the priming loop (gray) and intrusion loop (bright orange) in NDV L-P complex. d Comparison of the NDV (green), PIV5 (blue, PDB: 6V85), hMPV (yellow, PDB: 6U5O), and VSV (light pink, PDB: 5A22) intrusion loops. The catalytic site is indicated by a red star. e, f Comparison of the NDV (green), PIV5 (blue), hMPV (yellow), and VSV (light pink) priming loops. The catalytic site is indicated by a red star. The right region is rotated 50° along the vertical axis.
