Fig. 5: Miniaturized ultrasound transducer-induced localized cavitation in blood vessel phantom.

a–c Ultrasound-induced microbubble fragmentation via our 3D printed miniaturized ultrasound transducer in a 3D printed blood vessel phantom. d Microbubble content vs. time, indicating that the fragmentation rate is related to the input voltage. e–h Localized drug delivery testing. The microbubbles can be controlled to fragment only at the focal area.