Fig. 5: Higher IFN-beta and IFN-lambda levels are associated with PASC. | Nature Communications

Fig. 5: Higher IFN-beta and IFN-lambda levels are associated with PASC.

From: Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+β7 integrin+ T cells and anti-SARS-CoV-2 IgA response

Fig. 5

The plasma levels of IFN-α2 (A), IFN-β (C) and IFN-λ2/3 (E) of HC (n = 37), non-PASC (n = 65) and PASC (n = 62) individuals and sub-divided by mild or severe acute disease (B and D for IFN-α2 and IFN-β, respectively). Spearman’s correlation between the percentage of IFN-λ2/3 and CD8+EOMES+ for non-PASC and PASC individuals (F). Data are shown in a scatter dot plot format as median ± IQR. Kruskal–Wallis test was applied to figures A, C and E to identify statistical differences followed by Dunn’s multiple comparisons test. A two-way ANOVA was used in figures B and D.

Back to article page