Fig. 6: The capacity of the biomineralized microbial nanocomposite for inhibiting tumor recurrence and metastasis in vivo. | Nature Communications

Fig. 6: The capacity of the biomineralized microbial nanocomposite for inhibiting tumor recurrence and metastasis in vivo.

From: Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virotherapy by augmenting tumor cell autophagy

Fig. 6

a Schematic illustration of the inhibiting tumor recurrence and metastasis investigation of the biomineralized microbial nanocomposite on TC-1-hCD46 xenograft tumor-bearing C57 female mice model. b Individual primary tumor growth kinetics in different groups. Data are presented as mean ± SD (n = 5 mice). Source data are provided as a Source Data file. c In vivo bioluminescence imaging of distant tumors metastasis. (n = 5 mice). d Individual distant tumor metastasis kinetics in different groups. Data are presented as mean ± SD (n = 5 mice). Source data are provided as a Source Data file. (G1: PBS, G2: OMVs@P2O-Ads, G3: CaP-OMVs-Ads, G4: Intra-Ads, G5:CaP-OMVs@P2O-Ads).

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