Fig. 6: Distribution of monoaminergic system genes. Presence/absence of monoamine pathway genes inferred using the reconciliation analysis. | Nature Communications

Fig. 6: Distribution of monoaminergic system genes. Presence/absence of monoamine pathway genes inferred using the reconciliation analysis.

From: The monoaminergic system is a bilaterian innovation

Fig. 6

Colours correspond to orthogroups, with darker shades indicating matches to specific InterProScan profiles (Supplementary Data 4). OG orthogroup, PAH phenylalanine hydroxylase, TPH tryptophan hydroxylase, TH tyrosine hydroxylase, DDC dopa decarboxylase, TDC tyrosine decarboxylase, HDC histidine decarboxylase, DBH dopamine beta hydroxylase, TBH tyramine beta hydroxylase, MOXD monooxygenase DBH-like, PNMT phenylethanolamine-N-methyltransferase, INMT indolethylamine-N-methyltransferase, NNMT nicotinamide-N-methyltransferase, VMAT vesicular monoamine transporter, VACHT vesicular acetylcholine transporter, GCH GTP cyclo-hydrolase, SLC solute ligand carrier, MAO monoamine oxidase, HNMT histamine-N-methyltransferase, SERT serotonin transporter, IDAT invertebrate dopamine transporter, 5HT3R 5-hydroxytryptamine receptor 3, INE Drosophila melanogaster transporter Ine, COMT catechol-O-methyltransferase, GPCR g-protein coupled receptor. Source Data are available at [https://figshare.le.ac.uk/articles/dataset/Monoamine_Neuromodulation_is_a_Bilaterian_Innovation_Results/20391477] in Results/Broccoli labelled table_OGs_protein_names.txt and in Results/InterProScan labelled *_IPS.tsv.

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