Fig. 1: Loss of Uhrf1 inhibits 3D growth of primary mouse NSCLC spheroids. | Nature Communications

Fig. 1: Loss of Uhrf1 inhibits 3D growth of primary mouse NSCLC spheroids.

From: UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma

Fig. 1

a Schematic representation of the pooled RNAi screens in primary spheroids and LKR10 cells. b Plot of shRNAs depleted from the cell population between T2 and T1 in primary mouse spheroids (y-axis) and murine LKR10 cells grown as monolayers (x-axis). Change in shRNA representation is shown as log2 fold change (log2FC). Uhrf1-specific shRNAs are indicated in red.

Back to article page