Fig. 7: Oncoplot and barplots of top somatic mutations. | Nature Communications

Fig. 7: Oncoplot and barplots of top somatic mutations.

From: Molecular profiling of aromatase inhibitor sensitive and resistant ER+HER2- postmenopausal breast cancers

Fig. 7

a Oncoplot of top mutated genes (>1%) with all patients in substudy with top barplot showing tumour mutation burden. Barplots of top 10 genes showing differences between % mutated in GRs and PRs ESR1HIGH (b) and mutated in GRs and PRs ESR1Low (c). Ranking of genes, p-values and adjusted p-values based on mafCompare function in maftools. Plots include variant classifications (frame-shift deletions—blue, frame-shift insertions—purple, missense—green, nonsense—red, nonstop—light blue, splice site—orange, in-frame deletion—yellow, in-frame insertion—dark red, and multi-hit—black). Source data are provided as a Source data file.

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