Table 1 Detailed statistics for Fig. 1
From: Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice
Statistical test | Factor | n | Statistic | 95% confidence interval | p value (adjusted where appropriate) | Corresponding figure | |
|---|---|---|---|---|---|---|---|
A | Male Saline = 6 Male AMPH = 6 Female Saline = 8 Female AMPH = 9 | Fig. 1d | |||||
Two-way ANOVA | Interaction | F (1, 25) = 5.452 | 0.0279 | ||||
Sex | F (1, 25) = 0.8604 | 0.3625 | |||||
Treatment | F (1, 25) = 3.695 | 0.066 | |||||
Sidak’s multiple comparisons test | Saline vs. AMPH within Male | t(25) = 2.782 | 0.03866 to 0.4946 | 0.0201 | |||
Sidak’s multiple comparisons test | Saline vs. AMPH within Female | t(25) = 0.3204 | −0.2177 to 0.166 | 0.9382 | |||
B | Male Saline = 6 Male AMPH = 6 Female Saline = 8 Female AMPH = 9 | Fig. 1e | |||||
Two-way ANOVA | Interaction | F (1, 25) = 7.551 | 0.011 | ||||
Sex | F (1, 25) = 3.618 | 0.0687 | |||||
Treatment | F (1, 25) = 2.595 | 0.1197 | |||||
Sidak’s multiple comparisons test | Saline vs. AMPH within Male | t(25) = 2.849 | −0.6597 to −0.05928 | 0.0172 | |||
Sidak’s multiple comparisons test | Saline vs. AMPH within Female | t(25) = 0.8827 | −0.1589 to 0.3464 | 0.6227 | |||
C | Male Saline = 6 Male AMPH = 6 | Fig. 1f | |||||
Pearson r | Dcc and miR-218 | r = −0.5129, r2 = 0.2631 | −0.8397 to 0.08641 | 0.0441 | |||
D | Female Saline = 8 Female AMPH = 9 | Fig. 1g | |||||
Pearson r | Dcc and miR-218 | r = −0.01114, r2 = 0.000124 | −0.4892 to 0.472 | 0.4831 | |||
E | Male Saline = 8 Male AMPH = 8 Female Saline = 9 Female AMPH = 10 | Fig. 1i | |||||
Two-way ANOVA | Interaction | F (1, 31) = 6.212 | 0.0182 | ||||
Sex | F (1, 31) = 9.524 | 0.0042 | |||||
Treatment | F (1, 31) = 0.7422 | 0.3956 | |||||
Sidak’s multiple comparisons test | Saline vs. AMPH within Male | t(31) = 1.107 | −0.3724 to 0.1339 0.01271 to 0.478 | 0.4768 | |||
Sidak’s multiple comparisons test | Saline vs. AMPH within Female | t(31) = 2.478 | 0.0373 | ||||
F | Male Saline = 8 Male AMPH = 8 Female Saline = 9 Female AMPH = 10 | Fig. 1j | |||||
Two-way ANOVA | Interaction | F (1, 31) = 6.602 | 0.0152 | ||||
Sex | F (1, 31) = 1.774 | 0.1925 | |||||
Treatment | F (1, 31) = 0.01128 | 0.9161 | |||||
Sidak’s multiple comparisons test | Saline vs. AMPH within Male | t(31) = 1.673 | −0.1911 to 1.135 | 0.198 | |||
Sidak’s multiple comparisons test | Saline vs. AMPH within Female | t(31) = 1.977 | −1.122 to 0.09665 | 0.1107 | |||
G | Male Saline = 8 Male AMPH = 8 | Fig. 1k | |||||
Pearson r | Dcc and miR-218 | r = −0.27, r2 = 0.07289 | −0.6753 to 0.2606 | 0.1559 | |||
H | Female Saline = 9 Female AMPH = 10 | Fig. 1l | |||||
Pearson r | Dcc and miR-218 | r = −0.4763, r2 = 0.2268 | −0.765 to −0.02813 | 0.0196 |
