Fig. 1: Ketone synthesis. | Nature Communications

Fig. 1: Ketone synthesis.

From: Ketones from aldehydes via alkyl C(sp3)−H functionalization under photoredox cooperative NHC/palladium catalysis

Fig. 1

a Classical ketone synthesis from alcohols and acyl electrophiles. b Ketone synthesis via TM-catalyzed coupling with aldehydes. c Ketone synthesis via NHC-catalyzed acylation of activated alkylation reagents. d This work: ketone synthesis via photoredox NHC/Pd-catalyzed acylation of alkyl C(sp33)-H. X = halide. TM = transition metal. NHC = N-heterocyclic carbene. NHPI = N-hydroxyphthalimide. hv = photoirradiation. RN = reaction.

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