Fig. 2: Differential expression analysis.
From: Next generation pan-cancer blood proteome profiling using proximity extension assay
a Volcano plots summarizing the differential expression results for AML, colorectal, glioma, and ovarian cancer. Corresponding results for all 12 cancers are shown in Fig. S2. P-values are calculated using a two-sided t-test, with Benjamini-Hochberg multiple hypothesis correction. b Barplot showing the number of proteins significantly upregulated, significantly downregulated, or with no significant differential expression for all cancer types. c Upset plot showing the number of upregulated proteins shared by the different cancer types. The top barplot shows the total number of upregulated proteins per cancer. Source data are provided as a Source data file. AML acute myeloid leukemia, CLL chronic lymphocytic leukemia, DLBCL diffuse large B-cell lymphoma.
