Fig. 5: Catalytic mechanism of the Fmoc-K/GMP/Cu2+ complex.
From: A supramolecular metalloenzyme possessing robust oxidase-mimetic catalytic function
a Density functional theory model of the dicopper/O2 reactive intermediate. Inset illustrates the coordination bonding between the copper and O and N atoms. b Proposed catalyzed turnover by the dicopper-mimetic site, including the reduction of the dicopper site, reaction with O2, cleavage of the peroxide bond and the reduction of O2 to water. States i and iii were obtained from DFT calculations. N, O, C, H and Cu atoms are indicated in blue, red, dim gray, light gray and orange, respectively.
