Fig. 7: Reductive cleavage of the diastereomers toward enantiodivergence.
From: Rhodium-catalyzed enantioselective and diastereodivergent access to diaxially chiral heterocycles
Reaction conditions: (S,S) or (R, R) diastereomer (0.1 mmol), HMPA (100 μL), and SmI2 (25 equiv) in THF at –78 oC.
