Fig. 1: Architecture of Arabidopsis thaliana SOS1.

a, b Overall structure of the dimeric model of SOS1 from two perpendicular views, parallel to the membrane plane. The two protomers in a are colored in deepsalmon and blue, respectively. Gray lines represent boundaries of the cell membrane. The N- and C-termini of the model are labeled. HC1 helix forms an angle of approximately 15 degrees with the plane of the membrane. The two protomers in b are shown as cartoon and surface representations. The protomer in the cartoon is colored in rainbow. The height and width of the structure are indicated. c Domain structure and organization of SOS1, numbers of amino acid defining the domains are indicated. Dashed line indicated the unresolved disorder regions in the structure. d Structure of the transmembrane ___domain viewed from the extracellular side. Core and dimerization domains are shown in cartoon and cylindrical representations, respectively. One core ___domain is shaded within a light blue oval. e The dimeric assembly of α-CTD viewed from the extracellular side.