Fig. 3: Tryptamine and phenethylamine are negatively correlated with the improvement of insulin sensitivity in dietary fiber-treated patients with type 2 diabetes. | Nature Communications

Fig. 3: Tryptamine and phenethylamine are negatively correlated with the improvement of insulin sensitivity in dietary fiber-treated patients with type 2 diabetes.

From: Gut microbiota-derived tryptamine and phenethylamine impair insulin sensitivity in metabolic syndrome and irritable bowel syndrome

Fig. 3

A, B Tryptamine and phenethylamine levels in fecal samples from T2D subjects in the control group (U group; n = 16) and high-fiber group (W group; n = 27) (Day 0 and Day 84). C, D Spearman’s correlation analysis between fecal tryptamine and phenethylamine level and HOMA-IR index in T2D subjects consuming a high fiber diet (W group; n = 27). Differences in phenethylamine and tryptamine levels in serum and fecal samples were analyzed by one-tailed ordinary two-way ANOVA or Student’s t-test. Data are presented as mean ± S.D. See additional information in Fig. S3.

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