Fig. 1: Expression of LeY in human prostate cancer. | Nature Communications

Fig. 1: Expression of LeY in human prostate cancer.

From: Low-dose carboplatin modifies the tumor microenvironment to augment CAR T cell efficacy in human prostate cancer models

Fig. 1

a The percentage of primary tumors (n = 709) or metastatic tumors (n = 30) positive for membrane LeY expression. Tumors were considered positive with \(\ge\)10% membrane LeY-positive cells. b Representative images of immunohistochemical staining of LeY in PDXs showing negative (0%), low (<10%), moderate (10–50%), and high (>50%) membrane LeY expression (scale bars = 25 µm). c The percentage of cells positive for low intensity (+1; yellow), moderate intensity (+2; orange), and high intensity (+3; red) membrane LeY expression in PDXs from the MURAL cohort. Staining was repeated on three generations of PDX tissue, and results from the latest generation are shown. NE neuroendocrine. Source data are provided as a Source Data file.

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