Fig. 3: Protection of mRNA vaccination for virus challenge. | Nature Communications

Fig. 3: Protection of mRNA vaccination for virus challenge.

From: mRNA vaccines encoding fusion proteins of monkeypox virus antigens protect mice from vaccinia virus challenge

Fig. 3

a Virus-challenge protection. At day 36, mice were intranasally challenged with a lethal dose (1 × 106 PFU) of WR vaccinia virus. The body weight of each mouse was examined daily post virus challenge, and the changes were calculated and compared with the initial weight. n = 5 biologically independent mice. b Viral load in the lungs. The lungs were collected on day 4 in the DPBS group or on day 9 post virus inoculation in other groups. Virus titers were examined by plaque assay. n = 5 biologically independent mice.

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