Fig. 1: Overall architecture of yeast SPT complexes. | Nature Communications

Fig. 1: Overall architecture of yeast SPT complexes.

From: Structure of the ceramide-bound SPOTS complex

Fig. 1

a Cryo-EM density map and model of the C2 symmetric yeast SPOT dimer at 3.4 Å resolution. b The map and the model of the monomeric SPOT complex at 3.4 Å resolution. The middle inset shows the local densities for 44:0;4 ceramide and PLP-K366. The contact diagram of the subunits within the complex is displayed on the right. The thickness of each line in the contact diagrams is proportional to the contact area between subunits. c The monomeric SPOTS complex at 3.3 Å resolution. The contact diagram is shown on the right and the local densities for 44:0;4 ceramide and PLP-K366 are in the middle. All individual subunits are consistently colored: Lcb1 in blue, Lcb2 in green, Orm1 in orange, Tsc3 in yellow, and Sac1 in purple. The membrane plane is indicated in gray.

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