Fig. 9: DI induces a sedentary-like bone metabolism shift. | Nature Communications

Fig. 9: DI induces a sedentary-like bone metabolism shift.

From: Comprehensive assessment of physiological responses in women during the ESA dry immersion VIVALDI microgravity simulation

Fig. 9

a Evolution of bone blood markers: total calcium, C-terminal crosslinked telopeptide of type I collagen (CTx), procollagen type I N-terminal propeptide (P1NP), intact osteocalcin (OC), and its carboxylated (Gla-OC) and undercarboxylated (Glu-OC) forms (n = 18). b Hypothesis schema of the DI effects on bone metabolism loop. Box plots indicate minimum, 25th percentile, median, 75th percentile, and maximum. a One-way RM ANOVA with post hoc Bonferroni multiple comparisons compared with BDC. Global ANOVA results: total calcium P < 0.001, serum CTx P < 0.001, serum P1NP P < 0.001, serum intact OC P < 0.001, serum Gla-OC P < 0.001, serum Glu-OC P < 0.001. Shading indicates DI period.

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