Fig. 2: Longitudinal analysis of LLL-specific CD8+ T cells in the blood of convalescent subjects. | Nature Communications

Fig. 2: Longitudinal analysis of LLL-specific CD8+ T cells in the blood of convalescent subjects.

From: SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors

Fig. 2

a Overview of the approximate timepoints for multiple visits of convalescent subjects. b Anti-nucleocapsid IgG titers at multiple time points (pink = visit 1, green = visit 2, orange = visit 3 used for this figure). Subjects with multiple visits are connected with black trendlines. The overall trend line (purple) across time points for each subject were generated by the mixed effect linear regression model (adjusted for age and sex) for the convalescent cohort with error bounds indicating a 95% confidence interval (light gray) n = 145. c Frequency of ALN-tetramer positive CD8+ T cells at multiple time points (red = visit 1, green = visit 2, blue = visit 3). Multiple visits for a single subject are connected by thin black lines. The overall purple trend line across time points for each subject were generated by the mix effect linear regression model (adjusted for age and sex) for the convalescent cohort with error bounds indicating a 95% confidence interval (light gray), n = 78. d Frequency of LLL-tetramer positive CD8+ T cells at multiple time points. e Frequency of LAL-tetramer positive CD8+ T cells at multiple time points.

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