Fig. 3: Levels of plasma biomarkers in cohort 1 at baseline.
From: Plasma biomarkers predict Alzheimer’s disease before clinical onset in Chinese cohorts
Plasma levels of Aβ42 (a), Aβ40 (b), Aβ42/Aβ40 (c), t-tau (d), p-tau181 (e), and NfL (f) were measured in cohort 1 at baseline. P-values and Bonferroni-corrected P-values (PBon) from two-sided Student’s t-test comparing participants with PreAD (orange dots) and normal controls (blue dots) are shown separately in each panel. Box ends represent the 25th and 75th percentiles, and the horizontal line within each box indicates the median. Whiskers extend to the upper and lower adjacent values or the most extreme points within the 1.5 × interquartile range of the 25th and 75th percentiles. n = 123 (control), 126 (PreAD). Aβ amyloid-β, Bon Bonferroni, NfL neurofilament light chain, PreAD preclinical Alzheimer’s disease, p-tau phosphorylated tau, t-tau total tau. Source data are provided as a Source Data file.
