Fig. 2: Static and time-resolved structure determination. | Nature Communications

Fig. 2: Static and time-resolved structure determination.

From: A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers

Fig. 2

Left panel: Static structure determination. Electron density (2Fo-Fc,) around residue TYR53 of lysozyme using serial data collected with (A) LCP and (B) HEC as delivery. Blue grid representation indicates a sigma level of 1.5. Right panel: time-resolved photoactivation of KR2. C Difference electron density maps (FoLight–FoDark) shown at sigma level of 3.0 depicting the structural changes of and around the retinal 1 μs after photoactivation.

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