Fig. 2: Only 12 genes are sufficient to replace chrXIIL for viability.
From: Building a eukaryotic chromosome arm by de novo design and synthesis
a Schematic diagram of the method for chromosomal truncation. b Tetrad analysis of heterozygous diploid strains with different chrXIIL truncations. c Fitness tests of strains carrying yll002w and yll006w deletion. WT: BY4742. d Tetrad analysis of heterozygous diploid strains with one chrXIIL removed. YLL002W (green) and YLL006W (purple) were integrated into the neochromosomes respectively or together. Red circle, the spores containing chrXIILΔ and the neochromosome.
