Fig. 9: Antibody response in 2-month-old infants from single-cell cohort.

a Heatmap representing the proportion of cells per time point and subcluster (SC) for each individual infant. The color key on the left represents cell-type immune associations, and the color key on the top represents the infant’s serologic response associations. b Heatmap representing the average interferon score per time point and SC for each individual infant. The color key on the left represents cell-type immune associations, and the color key on the top represents the infant’s serologic response associations. An asterisk (*) indicates a significant difference of p < 0.05, calculated by a two-sided t-test comparing post-vaccination (time points B and C) interferon scores versus the baseline (time point A).