Fig. 2: The preparation and characteristics of anti-VEGFR2 F(ab′)2-SS31. | Nature Communications

Fig. 2: The preparation and characteristics of anti-VEGFR2 F(ab′)2-SS31.

From: Anti-VEGFR2 F(ab′)2 drug conjugate promotes renal accumulation and glomerular repair in diabetic nephropathy

Fig. 2

a The construction and synthesis of anti-VEGFR2 F(ab′)2-SS31. Reproduced with permission from ref. 17. Copyright 2018, Oxford University Press. MS data of (b) anti-VEGFR2 F(ab′)2 and (c) anti-VEGFR2 F(ab′)2-SS31 reduced by TCEP. Detection range from 18 to 30 kD. d SDS-PAGE gel of anti-VEGFR2, anti-VEGFR2 F(ab′)2 and anti-VEGFR2 F(ab′)2-SS31. e Western blotting analysis of the binding ability of different samples to mouse VEGFR2. The experiments in d and e were repeated independently for three times with similar results. VEGFR2 vascular endothelial growth factor receptor 2, IgG immunoglobulin. Source data are provided as a Source Data file.

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