Fig. 5: The correlation between p-S937-GLI1/p-p38 levels and overall survival rates of children with MBSHH. | Nature Communications

Fig. 5: The correlation between p-S937-GLI1/p-p38 levels and overall survival rates of children with MBSHH.

From: Phosphorylation of human glioma-associated oncogene 1 on Ser937 regulates Sonic Hedgehog signaling in medulloblastoma

Fig. 5

a Representative immunohistochemistry images showing clinical non-Wnt/non-SHH and MBSHH samples stained with indicated antibodies. Bar, 50 μm. b, c Semi-quantification of p-S937-GLI1 and p-p38 in clinical non-Wnt/non-SHH and MBSHH sections (each dot represents one clinical specimen, data were pooled from ≥3 experiments, n = 20 for non-Wnt/non-SHH and n = 26 for MBSHH.). d Linear regression analysis between p-S937-GLI1 and p-p38. e, f Cumulative survival rates of 26 MBSHH cases with high or low levels of cytosolic p-S937-GLI1 or p-p38. Median survival times are shown. Data were presented as mean ± sd, two-tailed Student’s t test for (b, c), Pearson product-moment correlation coefficient analysis for (d), Log-rank analysis for (e, f). Source data are provided as a Source Data file.

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