Fig. 2: Paracrine signalling between CSCs and cancer cell subpopulations. | Nature Communications

Fig. 2: Paracrine signalling between CSCs and cancer cell subpopulations.

From: The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms

Fig. 2

a Paracrine signalling between CSCs (PDAC Cluster 1) and cancer cell subpopulations in PDAC patient primary tumours. b Paracrine signalling between ligand-receptor pairs mediating the paracrine crosstalk between CSCs (PDAC Cluster 1) and cancer cell subpopulations in PDAC patient primary tumours. c Cell type annotation in PDAC patient tumour sample RNA-sequencing data. Epithelial cells mark cancer cells. d WNT ligand and FZD5/6 expression in PDAC patient tumours based on single-cell RNA-sequencing.

Back to article page