Fig. 5: Drug target Mendelian randomisation pathways.
From: Comparing the effects of CETP in East Asian and European ancestries: a Mendelian randomization study
Nodes are presented in bold face, with G representing a genetic variant, \({{{{{\boldsymbol{P}}}}}}\) a protein drug target, \({{{{{\boldsymbol{X}}}}}}\) a biomarker, \({{{{{\boldsymbol{D}}}}}}\) the outcome, and \({{{{{\boldsymbol{U}}}}}}\) (potentially unmeasured) common causes of both \({{{{{\boldsymbol{P}}}}}}\), \({{{{{\boldsymbol{X}}}}}}\), \({{{{{\boldsymbol{D}}}}}}\). Labelled paths represent the effect magnitudes between nodes.
