Fig. 3: Rab-binding subunits of CORVET compared to HOPS. | Nature Communications

Fig. 3: Rab-binding subunits of CORVET compared to HOPS.

From: Structure of the endosomal CORVET tethering complex

Fig. 3

A Structural alignment of CORVET Vps3 (violet, AlphaFold prediction) with HOPS Vps39 (dark green, AlphaFold prediction). B Structural alignment of CORVET Vps8 (pink, cryo-EM structure from this study) with HOPS Vps41 (light green, AlphaFold prediction). C Vps8 subunit colored by conservation according to the sequence alignment with Vps41. In (A–C), the models of proteins are fitted into the semi-transparent volume (black outline) generated from the CORVET structure.

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