Fig. 5: In vitro anti-infective properties of various hemostatic materials. | Nature Communications

Fig. 5: In vitro anti-infective properties of various hemostatic materials.

From: Superporous sponge prepared by secondary network compaction with enhanced permeability and mechanical properties for non-compressible hemostasis in pigs

Fig. 5

a Schematic showing the antibacterial mechanism of alkylated-superporous chitosan sponge (A-spCS). b, c Photographs of colonies of E. coli. and S. aureus grown on LB agar plates after contact with blank, gauze, GS, CELOX, CELOX-E, chitosan sponge (CS), porous chitosan sponge (pCS), superporous chitosan sponge (spCS), and A-spCS. d, e Corresponding statistical results of log reduction of E. coli. and S. aureus. f Fluorescence microscopy images of live-dead staining of 3T3 fibroblasts after 1, 2, and 3 days of culture in A-spCS extract (n = 3). g The MTT tests revealed the cell viability of 3T3 fibroblasts cultured in different mass fractions (10, 20, 30, 40 mg/mL) of A-spCS extracts. h Hemolysis tests of Gauze, GS, CELOX, CELOX-E, CS, pCS, spCS and A-spCS. Values and error bars in (d, e, g, h) represent the mean and standard deviation (n  =  3 independent samples), P > 0.05 (ns), **P < 0.01, ***P < 0.001, ****P < 0.0001 (one-way ANOVA to compare multiple groups or two groups).

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