Fig. 1: Evolutionary relationships and genetic similarity of human and avian N2 neuraminidases from 1957 to 2019. | Nature Communications

Fig. 1: Evolutionary relationships and genetic similarity of human and avian N2 neuraminidases from 1957 to 2019.

From: A(H2N2) and A(H3N2) influenza pandemics elicited durable cross-reactive and protective antibodies against avian N2 neuraminidases

Fig. 1

a Maximum likelihood phylogenetic tree with branches colored by host and subtype. Representative strains used for serological testing are labeled, and abbreviations used in this study are shown in bold. b Heatmap of pairwise comparison of amino acid sequence similarities for human and avian N2 strains between 1957 to 2019, generated by using “ComplexHeatmap” package in R. Annotation on the right represents the NA amino acid sequence similarities, representative strains and year of virus isolation. Highly similar sequences between avian and human N2 are boxed.

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