Fig. 1: Behavioral analysis workflow and group-average longitudinal change in myelin-sensitive Magnetic Transfer (MT). | Nature Communications

Fig. 1: Behavioral analysis workflow and group-average longitudinal change in myelin-sensitive Magnetic Transfer (MT).

From: Longitudinal variation in resilient psychosocial functioning is associated with ongoing cortical myelination and functional reorganization during adolescence

Fig. 1

A Based on the Neuroscience in Psychiatry Network (NSPN) cohort, resilient psychosocial functioning (ResPSF) scores were computed for each subject at each available time point by predicting psychosocial distress (left) from adversity assessments (Alabama parenting questionnaire (APQ), Life events questionnaire (LEQ), Childhood trauma questionnaire (CTQ), Measure of Parenting style (MOPS), and socio-economic status (SES)). ResPSF scores were defined as the difference between observed and predicted distress, i.e., showing higher (i.e., more susceptible) or lower (i.e., more resilient) than expected psychosocial distress. Longitudinal changes in ResPSF are depicted in the bottom panel for participants that are part of the neuroimaging (MRI) or solely behavioral (non-MRI) analyses. B (i) Mean and standard deviation (SD) of intra-individual change in myelin-sensitive Magnetic Transfer (∆MT) in the full imaging sample (n = 199). (ii) ∆MT averaged across the cortex and visualized for three age strata. (iii) Mean and SD of ∆MT across 10 intracortical depths and across the cortex. Line colors for (ii) and (iii) reflect age strata defined in the Middle panel.

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