Table 1 Diversity of transcripts expressed from the 20 genes characterized using ultra-deep targeted long-read sequencing (ONT nanopore and PacBio Iso-Seq)
Target genes | Number of isoforms (merged ONT and PacBio dataset) | Number of isoforms with AS events (total number of AS events) | ||||||
|---|---|---|---|---|---|---|---|---|
Classification | Coding potential | |||||||
All | Known | Novel | Coding | Non-coding | A5A3 | ES | IR | |
Abca149 | 44 | 34 | 10 | 43 | 1 | 30 (45) | 3 (3) | 0 (0) |
Abca750 | 82 | 36 | 46 | 81 | 1 | 56 (80) | 26 (47) | 1 (1) |
Ank151 | 54 | 44 | 10 | 44 | 10 | 31 (40) | 37 (116) | 0 (0) |
Apoe | 1408 | 13 | 1395 | 1348 | 60 | 1380 (2650) | 1303 (4316) | 11 (11) |
App52 | 1119 | 147 | 972 | 1074 | 45 | 909 (1436) | 1037 (5889) | 0 (0) |
Bin126 | 624 | 52 | 572 | 605 | 19 | 476 (700) | 571 (2821) | 0 (0) |
Cd3353 | 54 | 16 | 38 | 51 | 3 | 50 (91) | 52 (83) | 9 (10) |
Clu26 | 964 | 28 | 936 | 937 | 27 | 915 (1758) | 705 (3894) | 1 (1) |
Fus26 | 312 | 74 | 238 | 282 | 30 | 234 (292) | 281 (1428) | 36 (36) |
Fyn54 | 96 | 45 | 51 | 93 | 3 | 72 (98) | 79 (286) | 0 (0) |
Mapt55 | 111 | 22 | 89 | 72 | 39 | 94 (132) | 88 (404) | 0 (0) |
Picalm56 | 323 | 140 | 183 | 232 | 91 | 176 (206) | 310 (839) | 0 (0) |
Ptk2b57 | 672 | 85 | 587 | 667 | 5 | 513 (811) | 416 (1287) | 1 (1) |
Rhbdf258 | 18 | 12 | 6 | 18 | 0 | 9 (10) | 2 (2) | 0 (0) |
Snca59 | 725 | 14 | 711 | 281 | 444 | 690 (1382) | 712 (1732) | 1 (1) |
Sorl160 | 213 | 137 | 76 | 199 | 14 | 197 (280) | 94 (94) | 0 (0) |
Tardbp61 | 191 | 79 | 112 | 150 | 41 | 113 (157) | 188 (907) | 69 (69) |
Trem262 | 97 | 13 | 84 | 80 | 17 | 86 (152) | 90 (129) | 5 (5) |
Trpa163 | 4 | 4 | 0 | 4 | 0 | 1 (1) | 0 (0) | 0 (0) |
Vgf64 | 51 | 5 | 46 | 44 | 7 | 50 (75) | 37 (38) | 0 (0) |
