Fig. 2: Comparison of plasma N-antigen and IgG Spike antibody levels among those with and without post-acute sequelae of SARS-CoV-2 (PASC) over a 28-day period after symptom onset.
From: Early biological markers of post-acute sequelae of SARS-CoV-2 infection
a, b Estimated mean values and 95% confidence intervals are plotted for biological specimen among PASC and non-PASC groups at days 5, 9, 14, 21, and 28 for N-antigen (a) and IgG (b) using generalized estimating equations fit with independent correlation, identity linkage, and Gaussian distribution. Covariates included sex, age, vaccination status, and SARS-CoV-2 variant. Statistics are derived from 80 participants with N-antigen measurements and 48 unvaccinated participants with IgG measurements. Statistical significance was assessed using two-tailed tests. Statistically significant distributions include N-Ag at day 5 (p = 0.01), IgG spike antibody at day 5 (p = 0.04), and IgG spike antibody at day 9 (p = 0.03).
