Fig. 1: ESM-DBP is a DBP field-specific PLM by ___domain-adaptive pretraining based general protein language model, i.e., ESM2, on the DBP dataset.

a Data distribution of original ESM2 and DBP ___domain-specific knowledge; b The proportion of DBPs in the original pretraining dataset of ESM2, i.e., UniRef50; c The overall architecture of ESM-DBP. The protein structures are drawn using pymol81.