Fig. 1: Schematic illustration of RMn-NB-sensitized RT for triggering potent ISCV. | Nature Communications

Fig. 1: Schematic illustration of RMn-NB-sensitized RT for triggering potent ISCV.

From: Two-dimensional coordination risedronate-manganese nanobelts as adjuvant for cancer radiotherapy and immunotherapy

Fig. 1

a Schematically illustrating the preparation of RMn-NBs. b The mechanism of RMn-NBs as a visual nanoadjuvant for in situ vaccination of RT. Reactive oxygen species (ROS), glutathione (GSH), calreticulin (CRT), high mobility group protein B1 (HMGB1), adenosine triphosphate (ATP), dendritic cells (DCs), interferon-beta (IFN-β), interferon-gama (IFN-γ), hypoxia-inducible factor-1α (HIF-1α), vascular endothelial growth factor (VEGF), cyclic GMP-AMP synthase (cGAS), cyclic GMP-AMP (cGAMP), stimulator of interferon genes (STING). Created in BioRender. Luo, Z. (2024) BioRender.com/u37f450.

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