Fig. 5: RNA sequencing of CT26 tumor tissues treated with RMn-NBs and RT. | Nature Communications

Fig. 5: RNA sequencing of CT26 tumor tissues treated with RMn-NBs and RT.

From: Two-dimensional coordination risedronate-manganese nanobelts as adjuvant for cancer radiotherapy and immunotherapy

Fig. 5

a Venn plot indicates the gene expression relationship among groups (n = 3 mice). Differential gene volcano plots between (b) Saline and Saline + RT groups (n = 3 mice), (c) RMn-NBs and RMn-NBs + RT groups (n = 3 mice), (d) Saline + RT and RMn-NBs + RT groups (n = 3 mice), indicating the number of up- or down-regulated gene expressions. e GO enrichment analysis between Saline + RT and RMn-NBs + RT groups (n = 3 mice). f Differential gene clustering heatmap between Saline + RT and RMn-NBs + RT groups (n = 3 mice). Statistical analysis is performed using two-tailed Student’s t-test for comparing two groups, and one-way ANOVA analysis of variance for multiple groups. p > 0.05 represent nonsignificance, while p < 0.05 indicate statistical significance. The raw sequence data reported in this paper have been deposited in the Genome Sequence Archive (BioProject: PRJCA024822 and GSA: CRA019291).

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