Fig. 5: Synbiotic GOS and L. reuteri enriches pentadecanoic acid (C15:0) in mice. | Nature Communications

Fig. 5: Synbiotic GOS and L. reuteri enriches pentadecanoic acid (C15:0) in mice.

From: Galactooligosaccharides and Limosilactobacillus reuteri synergistically alleviate gut inflammation and barrier dysfunction by enriching Bacteroides acidifaciens for pentadecanoic acid biosynthesis

Fig. 5

a Heatmap of differentially enriched metabolites in the feces of mice supplemented with GOS and L. reuteri individually or in combination (n = 6 per group). b, c Volcano plot of differentially enriched metabolites among control, DSS and DSS + GL groups. d, e The fecal content of C15:0 or 9-pentadecanoic acid in DSS-treated mice with/without supplementation with the synbiotic GOS and L. reuteri (n = 6 per group). f–h The fecal content of C15:0 in DSS-treated mice with/without oral administration of fecal microbiota (FMT, n = 8 per group), Fecal cell-free supernatant (FST, n = 6 per group), or B. acidifaciens (n = 6 per group). One-way ANOVA with Tukey’s test was used for statistical analysis. Data were presented as mean ± SEM. Source data were provided as a Source Data file.

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