Fig. 2: Kinetics of inflammatory mediator expression during S. aureus biofilm infections.
From: Tissue niche influences immune and metabolic profiles to Staphylococcus aureus biofilm infection
Supernatants collected from craniotomy (brain and galea; red; n = 15 animals/group) and PJI (joint and soft tissue surrounding the knee; blue; days 3 and 7, n = 13; day 14, n = 14) homogenates were assayed for cytokine (A–F), chemokine (G–K), and growth factor (L) content using a MILLIPLEX MAP 25-plex assay with data normalized to protein content. Data pooled from three independent experiments and represent mean ± SEM. A–L Mixed-effects model with Geisser–Greenhouse correction and Tukey’s multiple comparison test. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. Source data are provided as a Source Data file.
