Fig. 3: Correlation of PCs with structural measures and cardiovascular diseaserisk factors.
From: Genetic basis of right and left ventricular heart shape
Plots summarising the Pearson’s correlation coefficient. Top is the correlation matrix between shape PCs and cardiovascular disease risk factors, below is the correlation matrix between shape PCs and CMR-derived measures of cardiac structure and function. (n = 39,538) In each correlation matrix the size of the circle indicates the p-value significance (the smallest circle is p < 0.05), and the colour of the circle indicates the strength of the Pearson’s correlation coefficient. The correlation test is two-sided in this analysis. PC, principal component; CMR, cardiovascular magnetic resonance; LV, left ventricular; RV, right ventricular; EDV, end-diastolic volume; ESV, end-systolic volume; SV, stroke volume; EF, ejection fraction; (LV/RV), ventricular mass; MVR, mass to volume ratio; BMI, body mass index; LDL, low density lipoprotein levels; HDL, high density lipoprotein levels; Triglyceride, blood triglyceride levels.
